Picture 4 : Leukoplakia on lower lip Figure 1: Homogeneous oral Leukoplakia in the left lateral border and ventrum of the tongue. Figure Leukoplakia can become pre-cancerous on the sun-exposed lower lip.

Figure 1: Homogeneous oral leukoplakia in the left lateral border and ventrum of the tongue. Figure 2: Non-homogeneous oral leukoplakia. White plaques intermixed with red patches. Figure 3: Proliferative verrucous leukoplakia: multifocal involvement affecting …

1) homogeneous leukoplakia, a lesion of uniform flat appearance that may exhibit superficial irregularities, but with consistent texture throughout; and 2) non-homogeneous leukoplakia, a predominantly white or white and red lesion (erythroleukoplakia) with an irregular texture that may present as a flat, nodular, or exophytic lesion. Two main clinical types of leukoplakia are recognized, being homogeneous and non-homogeneous leukoplakia. The distinction of these is purely clinical, based on surface colour and morphological (thickness) character-istics, and do have some bearing on the outcome or prognosis. Homogeneous lesions are uniformly ﬂat, thin A homogeneous leukoplakia on the left commissure extending posteriorly. In addition, typical alterations of potentially malignant lesions are seen co-existing in the margins of squamous cell carcinoma. Erythroleukoplakia can therefore be considered a variant of either leukoplakia or erythroplakia since its appearance is midway between. Leukoplakias are commonly homogeneous and most are benign.

Oral leukoplakia (leuko=white, plakia=patch) is a white patch in the mouth that There are two main types: homogenous and non-homogenous leukoplakia. homogeneous leukoplakia or minimal visible leukoplakia. In 2 patients (11%) malignant transformation occurred a mean of 1.75 years after bleomycin treat-ment. CONCLUSIONS. Topical bleomycin may prevent the potential progression of leu-koplakia through dysplasia to carcinoma. Close follow-up of all patients with dysplasia is required. Non-homogeneous leukoplakia has a greater risk of car-cinomatous transformation (20–25%) than homogeneous leukoplakia (0.6–5%) [11, 13].

homogeneous leukoplakia or minimal visible leukoplakia. In 2 patients (11%) malignant transformation occurred a mean of 1.75 years after bleomycin treat-ment. CONCLUSIONS.

A double-blind analysis. N Engl J Med 323: 290– Jimenez SY, Basterra AJ (1999). Oral lichen planus 294. plaques and homogeneous leukoplasia: comparative results Eisen D, Griﬃths CE, Ellis CN, Nickoloﬀ BJ, Voorhees JJ of treatment with CO2 laser. Acta Otorrinolaringol Esp 50: (1990b).

Nonhomogeneous leukoplakia, or so-called speckled leukoplakia or nodular leukoplakia - a predominantly white or white and red lesion (erythroleukoplakia) with an irregular texture that may be flat, nodular, exophytic, or papillary/verrucous - is more likely to be potentially malignant. The color may be predominantly white or a. Homogeneous leukoplakias: the most common type, are uniformly white plaques – common in the buccal (cheek) mucosa and usually of low malignant potential.

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. The study was approved by the Ethics Committee of the University of Valencia (Spain), and informed consent was obtained from each patient. The purpose of this study was to genotype strains of Candida albicans to determine whether specific types were associated with chronic hyperplastic candidosis (CHC). A total of 67 candidal isolates from CHC patients ( n = 17) and from patients with other oral conditions ( n = 21) were genotyped by PCR fingerprinting employing two interrepeat primer combinations (1245 and 1246 primers or 1251 Renstrup reported 32% of homogenous leukoplakia with no atypia were positive for Candida, whereas, 60% of speckled leukoplakia showed Candida hyphae with cellular atypia. In the present study, although 12 cases of leukoplakia were positive by culture, Gram stain and PAP-CFW stain could detect only seven and eight cases respectively, in A double-blind analysis.

6. Non -homogeneous leukoplakia It is white or white and red lesion ( erythroleukoplakia). Classically two clinical types of leukoplakia are recognised: homogeneous and nonhomogeneous, which can co-exist. Homogeneous leukoplakia is defined as a predominantly white lesion of uniform flat and thin appearance that may exhibit shallow cracks and that has a smooth, wrinkled or corrugated surface with a consistent texture throughout.
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Lesions can be multifocal, changing aspect and becoming elevated and/or rugous (especially in smokers).

Figure 16: Homogeneous leukoplakia on the ventral surface of the tongue. Figure 17A: Superadded candidiasis in a patient with homogeneous leukoplakia. Homogeneous OL arises as a white patch slightly elevated, thin, white to gray, uniform, and can present well defined borders or may gradually mix with normal adjacent mucosa (Figure 1 to 3).
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form of leukoplakia was apparent from the onset in all cases. However, in many patients who had homogeneous leukoplakias initially, an erythroplastic component ap- peared at varying times after the diagnosis. These changes could not be correlated with any evident factors. Multiple sites were handled statistically as one lesion.

Homogeneous leukoplakias: the most common type, are uniformly white plaques – common in the buccal (cheek) mucosa and usually of low malignant potential. Oral leukoplakia (leuko=white, plakia=patch) is a Figure 1: Homogeneous oral leukoplakia in the left lateral border and ventrum of the tongue.

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Homogeneous leukoplakia Non - Homogenous leukoplakia Speckled leukoplakia Nodular leukoplakia Verrucousleukoplakia Staging System [3] A clinical staging system for oral leukoplakia (OL system) on the lines of TNM staging was recommended by WHO in 2005 taking into account the size (L) and the histopathological features (P) of the lesion.

On being touched it appears leathery and dry with some superficial irregularities. Non-homogeneous leukoplakia: Here, the The color may be predominantly white or a. Homogeneous leukoplakias: the most common type, are uniformly white plaques – common in the buccal (cheek) mucosa and usually of low malignant potential.

HOMOGENEOUS LEUKOPLAKIA PDF. Non-homogenous leukoplakia is a lesion of non-uniform appearance. The color may be predominantly white or a. Homogeneous leukoplakias: the most common type, are uniformly white plaques – common in the buccal (cheek) mucosa and usually of low malignant potential. Oral leukoplakia (leuko=white, plakia=patch) is a

Principles of investigation and diagnosis 1. SECTION 1. HARD-TISSUE PATHOLOGY 2.

Fifty-six percent (N = 23) of the non-homogeneous type recurred. Among snuff-users 73% (N = 8) cases of OL recurred.